Methods

Forty six term, AGA infants with a family history for atopic disease fed from birth with a HA formula supplemented with LCPUFA (Aptamil HA 1, Milupa) and twenty five exclusively breast fed infants, constituted the case series. At three months of age the composition in AA and DHA of plasma and erythrocyte membrane phospholipids was determined on venous blood samples, after 3 hours fasting, bymeans ofgaschromatography. Differences between means for the two groups were analyzed. Statistical analysis was performed using Student's t-test. A value ofp < 0.05 was used for statistical significance.

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