Martin Raff Jim Apperly Toru Kondo YasuhitoTokumoto and

Dean Tang Timing cell-cycle exit and differentiation in oligodendrocyte development 100

'Discussion 107

Kim Nasmyth, Jan-Michael Peters and Frank Uhlmann Splitting the chromosome: cutting the ties that bind sister chromatids 113

Discussion 133

William Chia, Yu Cai, Xavier Morin, Murni Tio, Gerald Udolph, Fengwei Yu and Xiaohang Yang The cell cycle machinery and asymmetric cell division of neural progenitors in the Drosophila embryonic central nervous system 139 Discussion 151

General discussion III Determining organ size 158

Pierre Gönczy, Stephan Grill, Ernst H. K. Stelzer, Matthew Kirkham and Anthony A. Hyman Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos 164 Discussion 176

Peter J. Bryant Growth factors controlling imaginal disc growth in Drosophila 182 Discussion 194

General discussion IV Spatial organization and the cell cycle 200

Victor Ambros The temporal control of cell cycle and cell fate in Caenorhabditis elegans 203 Discussion 214

Jessica Greenwood,Vincenzo Costanzo, Kirsten Robertson, Carmel Hensey and Jean Gautier Responses to DNA damage in Xenopus: cell death or cell cycle arrest 221 Discussion 230

Martin Hobe, Ulrike Brand, Richard Waites and Rüdiger Simon Control of cell fate in plant meristems 235 Discussion 243

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