Organ Damage and Developmental Effects of Cytotoxic Therapy

The head and neck comprise a complex region with multiple tissue types, including mucosa, skin, subcutaneous tissue, salivary gland tissue, teeth, bone and cartilage. Each has a unique response to cytotoxic therapy. In general, two types of effects are seen. Acute effects that occur during or shortly after the course of treatment usually involve tissues that divide rapidly, resulting in erythema and pseudomembrane vs. ulceration of mucosa, erythema and desquamation of skin, reduced serous output from salivary glands and reduction of taste acuity. Cell populations in "late-reacting" tissues proliferate slowly and may not manifest injury until months to years after treatment. Early changes within these tissues may also occur but are usually not detected by standard methods of observation. Late changes,how-ever, can occur in all organs. Table 7.1 shows some of the more common late toxicities in relation to radiotherapy dose and type of chemotherapy.

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How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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