Major depressive disorder has an average lifetime prevalence of about 15 percent, with a twofold greater prevalence in women than men. Age of onset is generally after age 20 and before age 50. Onset after age 50 is associated with a higher incidence of structural brain lesions, including strokes and subcortical white-matter changes (Coffey et al., 1993). While single episodes are not rare, depression is generally considered a chronic, relapsing, and remitting illness. While periods of clinical normality are seen throughout the natural course of the disorder, recurrences occur with higher frequently and with greater intensity if episodes are not treated (Frank and Thase, 1999).
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Are You Depressed? Heard the horror stories about anti-depressants and how they can just make things worse? Are you sick of being over medicated, glazed over and too fat from taking too many happy pills? Do you hate the dry mouth, the mania and mood swings and sleep disturbances that can come with taking a prescribed mood elevator?