References

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1. Hales CN and Barker DJP, 1992, Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35: 595-601.

2. Hales CN, Barker DJP, Clark PMS, Cox LJ, Fall C, Osmond C & Winter PD, 1991, Fetal and infant growth and impaired glucose tolerance at age 64 years. Brit. Med. J. 303: 1019-1022.

3. Barker DJP, Hales CN, Fall CHD, Osmond C, Phipps K & Clark PMS, 1993, Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyper-lipideamia (syndrome X): relation to reduced fetal growth. Diabetologia 36: 62-67

4. Phillips DIW & Hales CN, 1996, The intrauterine environment and susceptibility to noninsulin dependent diabetes and the insulin resistance syndrome. The Diabetes Annual 10: 1-13

5. Neel JV (1962) Diabetes mellitus: "a thrifty" genotype rendered detrimental by "progress". AmJHum Genet 14: 353-362.

6. Poulsen P, Vaag A, Kyvik KO, Moller-Jansen, Beck-Nielsen H, 1997, Low birth weight is associated with non-insulin-dependent diabetes mellitus in discordant monozygotic and dizygotic twin pairs. Diabetologia 40: 439-446

7. Snoek A, Remacle C, Reusens B & Hoet JJ, 1990, Effect of a low protein diet during pregnancy on the fetal rat endocrine pancreas. Biol Neonate 57: 107-1 18.

8. Desai M & Hales C N, 1997, Role of fetal and infant growth in programming metabolism in later life. Biol. Rev 72: 329-348.

9. Hales CN, Desai M, Ozanne SE & Crowther NJ, 1996, Fishing in the steam of diabetes: From measuring insulin to the control of fetal organogenesis. Biochem Soc Trans 24: 341 -350.

10.Langley-Evans S & Jackson A, 1996, Intrauterine programming ofhypertension: Nutrient-hormone interactions. Nutrition Reviews 54 No 6: 163-169.

11 .Petry CJ, Ozanne SE, Wang CL & Hales CN, 1997, Early protein restriction and obesity independently induced hypertension in year old rats. Clin Science 93: 147-152.

12. Lucas A, Baker BA, Desai M & Hales CN 1996 Nutrition in pregnant or lactating rats programs lipid metabolism in the offspring. BritJNutrition 76: 605-612.

13.Burns SP, Desai, Cohen RD, Hales CN, Iles R4, Germain JP, Going TCH & Bailey RA, 1997 Glucogeogenesis, glucose handling, and structural changes in livers of the adult offspring of rats partially deprived of protein during pregnancy and lactaiton. J CIin Invest 100: 1768-1774.

I4.Ozanne SE & Hales CN (1999)

The Long term consequences of intrauterine protein malnutrition for glucose metabolism. Proc Nutr Soc. (In press).

15.de Lange T, 1998, Telomeres and senescence: Ending the debate. Science 279: 334-335.

16. Jennings BJ, Ozanne SE, Dorling MW & Hales CN, 1999, Early growth determines longevity in male rats and may be related to telomere shortening in the kidney. FEBS Letters 448( 1): 4-8.

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