Virion Structure

Whereas smaller DNA viruses, such as SV40, Polyoma, Papilloma and Adenoviruses, are nonenveloped, all the herpesviruses have an outer envelope and within this, a capsid that contains the viral DNA. By electron microscopy (EM), in composition and appearance EBV resembles a typical herpesvirus with a toroid-shaped protein core wrapped with genomic DNA, as shown in Figure 7. Its nucleocapsid is composed of 162 capsomeres and its outer envelope is made up of glycoprotein (gp) spikes, many of which are composed of a 220/350-kDa protein, the principal target of a virus-neutralizing antibody response. Size variation of this protein reflects the number of glycosylated amino acid residues it contains. To date, gp220/350 is still the prime candidate for producing an EBV vaccine that might prevent, or delay, infection in vivo. The high lipid content of the envelope results in relative instability of EB virions at room temperature, and their rapid inactivation by lipid solvents, such as ether and chloroform, or by detergents. This is another difference between the herpesviruses and the small DNA viruses, the latter being generally stable under these conditions. Between the nucleocapsid and the envelope is a region called the tegument, which is frequently distributed asymmetrically, and by EM shows no distinctive features. The composition of the tegument in EBV has been much less carefully studied than in some other herpesviruses, notably herpessimplex viruses.

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Body Detox Made Easy

Body Detox Made Easy

What exactly is a detox routine? Basically a detox routine is an all-natural method of cleansing yourbr body by giving it the time and conditions it needs to rebuild and heal from the damages of daily life and the foods you eat and other substances you intake. There are many different types of known detox routines.

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