The majority of patients with papillomas are asymptomatic. Some patients may complain of mild dysphagia. There is an association of papillomas with gastroesophageal reflux and peptic ulcer disease.1 ' Therefore, some patients may present indirectly with symptoms of these associated disorders. There are no characteristic findings on physical examination. Endoscopically fleshy pink-colored lesions, either sessile or pedunculated, are seen usually in the distal esophagus. Visually, the lesions may be mistaken for squamous carcinoma. The diagnosis is confirmed by biopsy. No further diagnostic or staging workup has been advocated.

Figure 23-8 Photomicrograph of squamous papilloma showing no dysplastic squamous epithelium with a central core of connective tissue.

TABLE 23-4 -- Classification of Esophageal Cysts

I. Congenital a. Duplication b. Bronchogenic a. Neuroenteric

III. Acquired a. Retention (single or multiple)

Data from Arbono, J.L., Fazzi, G.F., and Mayoral, J.: Congenital esophageal cysts: Case report and review of the literature. Am. J. Gastroenterol., 79:177, 1984.

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