Length Of Preclinical Studies

Determining the appropriate length of the preclinical study will be an important component of experimental design. Initially, relatively short studies involving several weeks or 1-2 months in duration could be performed in small animal models to test variables including transplantation sites, cell stability and migration. Such short-term studies will inevitably be followed by studies of several months' duration to determine therapeutic efficacy, viability, and stability of the transplanted stem cells and will have to be performed in both small and large animals.

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