smegmatis, P. aeruginosa and S. aureus for chloroform extracts, Proteus vulgaris for hexane extracts.66 Antimicrobial activity of different pressure liquid extraction (PLE) fractions of S. platensis was tested against S. aureus ATCC 25923, E. coli ATCC 11775, C. albicans ATCC 60193, and Aspergillus niger ATCC 16404.67. Data obtained demonstrated that the hexane and petroleum ether extracts were slightly more active than ethanolic extracts. Furthermore, aqueous extracts were inactive against the microorganisms tested. However, C. albicans was the most sensitive micro-organism to all Spirulina PLE extracts.67

The results of studies on the detection of biologically active substances in biomass dilutions and culture fluid of S. platensis and algae (Chlorella, Fucus, Laminaria) by the agar diffusion method are presented. After the sterilization of the solutions with chloroform, a substance with lysozyme-like activity and two substances with antagonistic activity deep in agar and on its surface were detected with the use of the micrococcal indicator strain.88

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