Group A: medication only, Group B: medication + Spirulina, Group C: Spirulina only ANOVA: * significant at p < .05.

a 2 months-4 months, significant at p < .05.

1 Baseline—4 months, significant at p < .001. c 2 months-4 months, significant at p < .01. d Baseline—4 months, significant at p < .01.

4 months (Table 4.7). Thus these findings suggest the beneficial effect of good quality proteins in improving the protein status in the Spirulina-supplemented groups as against the medication group (Group A).

The pulmonary function tests (PFT) namely, forced vital capacity (FVC), forced expiratory volume in first second (FEV1), peak expiratory flow rate (PEFR), and FEV1/FVC revealed an overall improvement in pulmonary function efficacy in all the three groups. The patients in Group A (only medication) showed a significant improvement in % FEV1 and % FEV1/FVC values over a period of 4 months (Table 4.8).

Majority of the patients (65%) in Group A were on both bronchodilators (like salbutamol, salmeterol, deriphylline, aminophylline) and anti-inflammatory drugs (such as budesonide, prednisone). Thus this conjunction therapy with bronchodilators and

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