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The Big Asthma Lie

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ANOVA: *p < .05, **p < .01, ***p < .001. *p < .05, **p < .01, ***p < .001 vs. 0 months.

ANOVA: *p < .05, **p < .01, ***p < .001. *p < .05, **p < .01, ***p < .001 vs. 0 months.

cardiovascular disease and identifies high-risk phenotypes in normocholesterolemic diabetic patients, the 12.3 mg% reduction induced by Spirulina is noteworthy.37

Analysis clearly highlights the improvement in the assortment of CHD risk factors with Spirulina supplementation. In diabetes, these risk factors often co-occur. A linear increase in the risk for CHD has been observed with an increase in the number of risk factors.19 Investigators now emphasize the measure of non-HDL-C since it serves as an index of combined risk of all the lipoprotein changes in diabetes.38 Striking reductions in the non-HDL-C levels were noticed in patients supplemented with Spirulina (Table 4.3), indicating a reduction in all the atherogenic apo B containing lipoproteins and therefore plausibly a reduced risk for CHD. These results added credence to the earlier observations highlighting the beneficial attributes of Spirulina.

Conclusions

In conclusion, improved metabolic control resulted in the correction of several risk factors that figure prominently in the etiology of CHD. The results for the current study therefore, strongly favors the use of Spirulina as an adjunctive therapy for the optimal management of diabetes.

therapeutic utility of spirulina in asthma

Introduction

Bronchial asthma is a disorder that affects lungs and the airways that deliver air to the lungs. It is the most common respiratory disorder characterized by episodic intrathoracic airway obstruction, airway hyperresponsiveness and airway inflammation. Spirulina with its galaxy of antioxidant nutrients can thus be an effective therapeutic mode for combating detrimental damage and inflammation in the respiratory lining. It could be an ideal choice in such a context for two reasons, first it is a rich source of GLA, which might play a crucial role as an anti-inflammatory agent, and second it has a good antioxidant profile that might help to counteract the detrimental exposure to oxidants.

A pilot trial carried out for a period of 2 months in the department revealed the beneficial role of Spirulina in the treatment of bronchial asthma.39 Thus with this background, the present study was undertaken further in this direction to explore the long-term effect of Spirulina supplementation for a period of 4 months in patients suffering from mild to moderate degree of bronchial asthma. Thus, the present study focused on the objective "to study the effect of Spirulina supplementation on the protein status, pulmonary function and IgE status of the asthma patients."

Methodology

The enrolled asthma patients (from Shri Sayajirao General Hospital, Vadodara) suffering from mild to moderate degree of bronchial asthma were categorized into three groups— Group A: the control group was kept only on medication for a period of 4 months, Group B: the experimental group was administered medication and Spirulina (1 g/day) for a period of 2 months after which the Spirulina was withdrawn for the next 2 months and the medication was continued; and Group C: also the experimental group that was administered only Spirulina (1 g/day) for a period of 4 months. The patient's in-group A and B were on bronchodilators and anti-inflammatory drugs and their medication was not altered during the intervention trial. The serum total protein, albumin, and globulin and IgE were analyzed at baseline and at the end of 2-and 4-month period.

Resultsand Discussion

The anthropometric measurement of the three groups of asthmatics is depicted in Table 4.5. The mean ages were 46, 40, and 33 years of Group A, Group B, and Group C asthmatics, respectively. The three groups were comparable with respect to height, weight, waist-hip ratio (WHR), and body mass index (BMI).

An overall good nutrition is very important in the prevention of asthma. The results from dietary analysis reveal that the patient's intake in all the three groups was inadequate with respect to proteins, fats, j-carotene and calories intake (Table 4.6).

This may play an additional triggering role in the ongoing asthma attacks by weakening body's immunity to fight infections and hence the recommended guideline is to satisfy the minimum daily requirements of all nutrients. Ahigh P/S ratio suggests a high intake of polyunsaturated fatty acids (PUFA) from the diet, which can be detrimental, leading to high release of free radicals. The fatty acid composition of the diet in particular, the relative amounts of n-6 and n-3 PUFA may also be associated with the risk of asthma.40 However, in the present study the dietary analysis revealed

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