Information pertaining to developmental toxicity can also be obtained from studies where animals are continuously exposed to the test substance over one or more generations.75
In our study, Spirulina was given to three generations over a period of approximately 2 years, following the schedule shown in Figure 2.1. Fertility, gestation, viability and lactation indices were recorded. A test of subchronic toxicity was carried out on the F3B generation.
Analyses of reproduction and lactation results showed no adverse effects from Spirulina on fertility or gestation or any other parameters usually considered in this kind of study76 (Table 2.3).
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