1. Mittal, A., Kumar, P.V., Banerjee, S., et al., Modulatory potential of Spirulina fusi-formis on carcinogen metabolizing enzymes in Swiss albino mice. Phytother Res 13, 111, 1999.
2. Mittal, A., Kumar, A., and Rao, A.R., Modulatory influence of Spirulina fusiformis on 7, 12-dimethylbenz(a)anthracene induced papillomagenesis in the skin of mice. Pharmaceutical Biol 36, 341, 1998.
3. Dasgupta, T., Banerjee, S., Yadav, P.K., et al., Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis. Mol Cell Biochem 226, 27, 2001.
Premkumar, K., Pachiappan, A., Abraham, S.K., et al., Effect of Spirulina fusiformis on cyclophosphamide and mitomycin-C induced genotoxicity and oxidative stress in mice. Fitoterapia 72, 906, 2001.
Premkumar, K., Abraham, S.K., Santhiya, S.T., et al., Protective effect of Spirulina fusiformis on chemical-induced genotoxicity in mice. Fitoterapia 75, 24, 2004. Vadiraja, B.B., Gaikwad, N.W., and Madyastha, K.M., Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicty in rats. Biochem Biophys Res Commun 249, 428, 1998. Miranda, M.S., Cintra, R.G., Barros, S.B., et al., Antioxidant activity of the microalga Spirulina maxima. Braz J Med Biol Res 31, 1075, 1998.
Wu, L.-C., Ho, J.A., Shieh, M.-C., et al., Antioxidant and antiproliferative activities of spirulina and chlorella water extracts. J Agric Food Chem 53, 4207, 2005. Khan, M., Shobha, J.C., Mohan, I.K., et al., Protective effect of Spirulina against doxorubicin-induced cardiotoxicity. Phytother Res 19, 1030, 2005. Khan, M., Varadharaj, S., Shobha, J.C., et al., C-phycocyanin ameliorates doxorubicin-induced oxidative stress and apoptosis in adult rat cardiomyocytes. J Cardiovasc Pharmacol 47, 9, 2006.
Bhat, V.B., and Madyastha, K.M., C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro. Biochem Biophys Res Commun 275, 20, 2000. Romay, C., Armesto, J., Remirez, D., et al., Antioxidant and anti-inflammatory properties of C-phycocyanin from blue-green algae. Inflamm Res 47, 36, 1998. Romay, C., and González, R., Phycocyanin is an antioxidant protector of human erythrocytes against lysis by peroxyl radicals. J Pharm Pharmacol 52, 367, 2000. Bhat, V.B., and Madyastha, K.M., Scavenging of peroxynitrite by phycocyanin and phycocyanobilin from Spirulina platensis: protection against oxidative damage to DNA. Biochem Biophys Res Commun 285, 262, 2001.
Hirata, T., Tanaka, M., Ooike, M., et al., Antioxidant activities of phycocyanobilin prepared from Spirulinaplatensis. J Appl Phycol 12, 435, 2000. Mohan, I.K., Khan, M., Shobha, J.C., et al., Protection against cisplatin-induced nephrotoxicity by Spirulina in rats. Cancer Chemother Pharmacol 58, 802, 2006. Khan, M., Shobha, J.C., Mohan, I.K., et al., Spirulina attenuates cyclosporine-induced nephrotoxicity in rats. J Appl Toxicol 26, 444, 2006.
Kuhad, A., Tirkey, N., Pilkhwal, S., et al., Renoprotective effect of Spirulina fusiformis on cisplatin-induced oxidative stress and renal dysfunction in rats. Ren Fail 28, 247, 2006.
Kuhad, A., Tirkey, N., Pilkhwal, S., et al., Effect of Spirulina, a blue green algae, on gentamicin-induced oxidative stress and renal dysfunction in rats. Fundam Clin Pharmacol 20, 121, 2006.
Chamorro, G., Pérez-Albiter, M., Serrano-García, N., et al., Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Nutr Neurosci 9, 207, 2006.
Rimbau, V., Camins, A., Romay, C., et al., Protective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampus. Neurosci Lett 276, 75, 1999.
Remirez, D., Fernández, V., Tapia, G., et al., Influence of C-phycocyanin on hepatocellular parameters related to liver oxidative stress and Kupffer cell functioning. Inflamm Res 5, 351, 2002.
Upasani, C.D., and Balaraman, R., Protective effect of Spirulina on lead induced deleterious changes in the lipid peroxidation and endogenous antioxidants in rats. PhytotherRes 17, 330, 2003.
24. Kumar, M., Sharma, M.K., and Kumar, A., Spirulina fusiformis: a food supplement against mercury induced hepatic toxicity. J Health Sci 51, 424, 2005.
25. Misbahuddin, M., Islam, A.Z., Khandker, S., et al., Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study. Clin Toxicol (Phila) 44, 135, 2006.
26. Kenyon, E.M., Del Razo, L.M., and Hughes, M.F., Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in mice following acute oral administration of arsenate. Toxicol Sci 85, 468, 2005.
27. Kala, S.V., Neely, M.W., Kala, G., et al., The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic. J Biol Chem 275, 33404, 2000.
28. Kala, S.V., Kala, G., Prater, C.I., et al., Formation and urinary excretion of arsenic triglutathione and methylarsenic diglutathione. Chem Res Toxicol 17, 243, 2004.
Was this article helpful?
All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.