Table 102

Percentage of Peritoneal Phagocytic Cells Ingesting Latex Particles From Mice Fed Spirulina

Splenic PFC Phagocytic cell

Means ± SD of 10 mice *p < .05, **p < .01 compared to Control. Source: Hayashi, O., J. Nutr. Sci. Vitaminol., 40, 435, 1994. With permission.

At the beginning of the study we used in-vivo and in-vitro systems to investigate whether S. platensis and its extracts enhance the immune response through primary response and macrophage function in mice. BALB/cAnNCrj mice used in the study were fed laboratory chow containing 10 or 20% (w/w) dried Spirulina. The mice gained body weight normally and consumed an equivalent amount of food and water compared to control mice during the experiment period of 7 weeks. The mice fed on Spirulina diet showed increased numbers of splenic antibody-producing cells, that is, plaque-forming cells (PFC) in the primary immune responses to sheep red blood cells (SRBC) (Table 10.1).12 Immunoglobulin G (IgG)-antibody producing cells (IgG-PFC) in the secondary immune response, however, was hardly affected except for hemagglutination (HA) titer without 2-mercaptoethanol (2-ME) treatment, suggesting that Spirulina affects immunoglobulin M (IgM) antibody synthesis in the initial phase of the immune response. Phagocytic activity of peritoneal-exuded macrophages from the mice was significantly enhanced (Table 10.2). Proliferations of spleen cells by T-cell mitogens, concanavalin A (Con A), and phytohemagglutinin (PHA) were

Was this article helpful?

0 0
My Life My Diet

My Life My Diet

I lost over 60 pounds and 4+ inches off my waist without pills, strenuous exercise, or any of the things that the diet experts tell you to do...and I did it in less than 4 months! If you have the desire, and can read through my e-book , then this is for you! I could have easily made it a lot more difficult, with stacks of information that people will never read, but why?

Get My Free Ebook


Post a comment