Table 112

Studies on Spirulina Antiviral Activity In Vivo

Animal model

HSV-1 corneal infection of hamsters

Zosteriform HSV-2 infection in mice

Zosteriform HSV-2 infection in mice

Polyhedrosis virus infection in the silkworm larvae Bombyx mori

Human patients with viral chronic hepatitis

Spirulina

Aqueous extract from S. platensis. Absorbed to solid food

Aqueous extract from S. maxima. Topical application

Aqueous extract from S. maxima. Orally administered

S. platensis by leaf dip method as a fed supplement. The resistance to viral infection was associated to a 29 kDa protein S. platensis as a food supplement for 1 month

Dose

100-500 mg/kg body weight, per day. For 7 days before viral infection 3 mg/kg body weight, twice per day. Immediately before infection and for 5 days after infection 3 mg/kg body weight, twice per day. Immediately before infection and for 5 days after infection At a concentration of 2-20%

Unknown

Reference

Hayashi, et al., 199311

Barron et al. (unpublished results)21

Barron et al. (unpublished results)21

Babu et al., 200522

Baicus and Tanasescu, 200225

HSV-1, herpes simplex virus type 1; HSV-2, herpes simplex virus type 2.

alga consumption has any beneficial effect either on AIDS symptoms or on preventing HIV infection.26

Table 11.2 presents a summary of the Spirulina studies in vivo.

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