Table 125

Antimicrobial Activity of S. platensis Volatile Components

Inhibition zone (mm)'

^g/disc Standard

Microorganism

Streptococcus faecalis ATCC 8043 Bacillus subtilis ATCC 6643 Staphylococcus aureus 6538/P Staphylococcus epidermidis ATCC 12228 Enterobacter aerogenes CIP 6069 Enterobacter cloacae ATCC 13047 Escherichia coli ATCC 11230 Pseudomonas aeroginosa ATCC 27853 Salmonella typhimurium CCM 583 Proteus vulgaris ATCC 6897 Candida albicans ATCC 10239

0.0075 0.015 Tob Nys

8 14 nt

7 13 nt

7 12 nt 9 10 nt a Zone of inhibition, including the diameter of the filter paper disc (6 mm); mean value of three independent experiments; Tob, tobramycin (10 ^g/disc); Nys, nystatin (30 ^g/disc); nt, not tested; G, gram reaction; —, no activity. * Ozdemir et al., (2004)

FIGURE 12.3 y-Linolenic acid.

Microalgae are seen as a good y-linolenic acid (GLA) resource; moreover, deciphering of gene sequences in cyanobacteria paved the way for biotechnolo-gical production of GLA. Whereas the antibacterial properties of a-linolenic acid from cyanobacteria are well established,28 those of y-linolenic acid have been little explored. Cohen et al. (1987) reported that the amount of total fatty acids is in the range 2.4-4.8% of dry weight and GLA content of the fatty acid varies from 8-31.7% in different Spirulina strains.

Asthana et al. (2006) revealed that the antibacterial activity of the GLA (25 ^g/mL) from the cyanobacterium to different bacterial strains revealed the sequence of inhibition zones (mm) as: Staphylococcus aureus (18) >E. coli (16) >Salmonella typhi (14) >Pseudomonas aeruginosa (12) >Enterobacter aerogenes (7). However, this sequence was slightly altered with the equivalent dose (25 ^g/mL) of GLA standard with reference to P. aeruginosa or E. coli, as both had almost the same sensitivity level. The apparent increase in sensitivity of the bacterial test strains

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