Inactive ■ cAMP-dependent protein kinase

Cell's response

Adenylyl Cyclase-cAMP Second Messenger System

Table 74-2 shows a few of the many hormones that use the adenylyl cyclase-cAMP mechanism to stimulate their target tissues, and Figure 74-7 shows the adenylyl cyclase-cAMP second messenger system itself. Binding of the hormones with the receptor allows coupling of the receptor to a G protein. If the G protein stimulates the adenylyl cyclase-cAMP system, it is called a Gs protein, denoting a stimulatory G protein. Stimulation of adenylyl cyclase, a membrane-bound enzyme, by the Gs protein then catalyzes

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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