Chapter

Hemostasis and Blood Coagulation 457

Events in Hemostasis 457

Vascular Constriction 457

Formation of the Platelet Plug 457 Blood Coagulation in the Ruptured

Vessel 458 Fibrous Organization or Dissolution of the

Blood Clot 458

Mechanism of Blood Coagulation

Conversion of Prothrombin to Thrombin Conversion of Fibrinogen to Fibrin—

Formation of the Clot Vicious Circle of Clot Formation Initiation of Coagulation: Formation of

Prothrombin Activator Prevention of Blood Clotting in the Normal Vascular System—Intravascular Anticoagulants Lysis of Blood Clots—Plasmin Conditions That Cause Excessive Bleeding in Human Beings Decreased Prothrombin, Factor VII, Factor IX,and Factor X Caused by Vitamin K Deficiency Hemophilia Thrombocytopenia Thromboembolic Conditions in the Human Being

Femoral Venous Thrombosis and Massive

Pulmonary Embolism Disseminated Intravascular Coagulation Anticoagulants for Clinical Use Heparin as an Intravenous Anticoagulant Coumarins as Anticoagulants Prevention of Blood Coagulation Outside the Body Blood Coagulation Tests Bleeding Time Clotting Time Prothrombin Time

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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