Composite Effects of Pco2 pH and Po2 on Alveolar Ventilation

Figure 41-7 gives a quick overview of the manner in which the chemical factors Po2, Pco2, and pH— together—affect alveolar ventilation. To understand this diagram, first observe the four red curves. These curves were recorded at different levels of arterial Po2—40 mm Hg, 50 mm Hg, 60 mm Hg, and 100 mm Hg. For each of these curves, the Pco2 was changed from lower to higher levels. Thus, this

Pco2 Ventilation Curve

Figure 41-6

Venous Po2
10 20 30 40 50 60 Alveolar Pco2 (mm Hg)

Figure 41-6

The lower curve demonstrates the effect of different levels of arterial Po2 on alveolar ventilation, showing a sixfold increase in ventilation as the Po2 decreases from the normal level of 100 mm Hg to 20 mm Hg. The upper line shows that the arterial Pco2 was kept at a constant level during the measurements of this study; pH also was kept constant.

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Essentials of Human Physiology

Essentials of Human Physiology

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