Info

R' — CH—COOH

Note in this reaction that the nitrogen of the amino radical of one amino acid bonds with the carbon of the carboxyl radical of the other amino acid. A hydrogen ion is released from the amino radical, and a hydroxyl ion is released from the car-boxyl radical; these two combine to form a molecule of water. After the peptide linkage has been formed, an amino radical and a carboxyl radical are still at opposite ends of the new, longer molecule. Each of these radicals is capable of combining with additional amino acids to form a peptide chain. Some complicated protein molecules have many thousand amino acids combined by peptide linkages, and even the smallest protein molecule usually has more than 20 amino acids combined by peptide linkages. The average is about 400 amino acids.

Other Linkages in Protein Molecules. Some protein molecules are composed of several peptide chains rather than a single chain, and these chains are bound to one another

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