Inulin Clearance Can Be Used to Estimate GFR

If a substance is freely filtered (filtered as freely as water) and is not reabsorbed or secreted by the renal tubules, then the rate at which that substance is excreted in the urine (Us x V) is equal to the filtration rate of the substance by the kidneys (GFR x Ps).Thus,

The GFR, therefore, can be calculated as the clearance of the substance as follows:

A substance that fits these criteria is inulin, a polysac-charide molecule with a molecular weight of about

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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