Iodine Is Required for Formation of Thyroxine

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To form normal quantities of thyroxine, about 50 milligrams of ingested iodine in the form of iodides are required each year, or about 1 mg/week. To prevent iodine deficiency, common table salt is iodized with about 1 part sodium iodide to every 100,000 parts sodium chloride.

Fate of Ingested Iodides. Iodides ingested orally are absorbed from the gastrointestinal tract into the blood in about the same manner as chlorides. Normally,

most of the iodides are rapidly excreted by the kidneys, but only after about one fifth are selectively removed from the circulating blood by the cells of the thyroid gland and used for synthesis of the thyroid hormones.

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Essentials of Human Physiology

Essentials of Human Physiology

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