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1 11 21 31 41 51 61 71 81 91 101 111 121 Echo planar image m = -0.0863 m = -0.129

1 11 21 31 41 51 61 71 81 91 101 111 121 Echo planar image

1 11 21 31 41 51 61 71 81 91 101 111 121 Echo planar image

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Figure 15.1. The top left panel (a) shows the pain ratings (visual analogue scale (VAS) 0-100) of the fibromyalgia patients to the stimulation of the back (black) or the finger (grey). The patients were stimulated in blocks of 20s with 20-s rest intervals. The top right (b) panel shows the same ratings for the healthy controls. The straight lines show the slope of the ratings. A negative slope indicates a reduction in pain rating and thus habituation and a positive slope indicates sensitization and increased pain ratings. The numbers to the right give the slope. The bottom panel (c) shows the difference in activation between the fibromyalgia patients (FMS) and the healthy controls related to the secondary somatosensory cortex. Note that the FMS patients show more activation both during the back and finger stimulation.

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