Preface

Neurorehabilitation is a medical specialty that is growing rapidly because medical advances have extended life expectancy and saved the lives of persons who previously would not have survived neurological injury. It is now urgent to develop a rigorous scientific basis for the field. The basic science relevant to functional recovery from neural injury is perhaps the most exciting and compelling of all the medical sciences. It encompasses areas of plasticity, regeneration and transplantation in the nervous system that individually have been the subjects of many monographs. With the Textbook of Neural Repair and Rehabilitation, these areas are integrated with each other and with the clinical topics to which they apply.

The Textbook of Neural Repair and Rehabilitation is organized into two volumes. Volume I, Neural Repair and Plasticity can stand alone as a textbook for graduate or advanced undergraduate level courses on recovery from neural injury. It is subdivided into two sections: Section A, Neural Plasticity and Section B, Neural Repair. Following an injury to the nervous system, most patients partially regain function. Section A, Plasticity, addresses the mechanisms that underlie spontaneous recovery as well as the added recovery induced by therapies based on use, retraining and pharmacological manipulations. The chapters cover the anatomical and physiological responses of neurons to injury, mechanisms of learning and memory, and plasticity in specific areas of the nervous system consequent to intense use, disuse and injury. Ultimately, interventions aimed at repairing the damaged neural circuitry will be required if full function is to be restored. Thus Section B, Neural Repair, covers topics on neuronal death, trophic factors, axonal regeneration and the molecules that inhibit it, stem cell biology, and cell transplantation. Section B builds on Section A because the mechanisms of plasticity will have to be invoked to translate restored neuronal connections into useful function.

Volume II, Medical Neurorehabilitation can stand alone as a clinical handbook for physicians, therapists, rehabilitation nurses and other neurorehabilita-tion professionals. It is organized into three sections. Section A, The Technology of Neurorehabilitation, is a direct transition from Volume I, emphasizing the applications of basic scientific principles to the practice of neurorehabilitation. This section includes material on functional imaging, motor control, gait and balance assessment, electrodiagnosis, virtual reality, and bioengineering and robotic applications to prosthetics and orthotics. Section B, Symptom-Specific Neurorehabilitation, provides guidelines to managing spasticity, gait disorders, autonomic and sexual dysfunction, cognitive deficits and other disabling neurological symptoms that are common to many disorders. Section C, Disease-Specific Neurore-habilitation, describes comprehensive approaches to the rehabilitation of persons suffering from the major categories of disabling neurological disorders, such as spinal cord injury, multiple sclerosis, stroke and neu-rodegenerative diseases.

Wherever possible, the chapters in this book refer the reader back to chapters that deal with relevant material at a different level. It is hoped that by stressing the integration of clinical and basic scientific knowledge, this book will help to advance the quality and scientific rigor of neurorehabilitation.

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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