Polymorphous Group

1.Hodgkin's disease. Specific lesions are very rare, but nonspecific dermatoses are rather commonly seen. *2. Mycosis fungoides a.Sezary's syndrome: This is a very rare form of exfoliative dermatitis (see Chap..23) that occurs at an early stage of a lymphoma. It is diagnosed by finding unusually large monocytoid cells (so-called Sezary cells) in the blood and in the skin. This cell is indistinguishable from the mycosis cell, both of which are derived from the T cell.

1. Leukemia: refers to circulating abnormal blood cells; may be seen along with lymphomas, but it is almost always associated with myelosis, such as myeloid leukemia. Cutaneous lesions are quite uncommon but may be specific or nonspecific.

VI. PSEUDOLYMPHOMA OF SPIEGLER-FENDT (SEE DICTIONARY-INDEX, FIG. 2C)

A benign, localized erythematous, nodular dermatosis usually on the face, with clinical and histologic features that make a distinction from lymphoma difficult. Some cases may eventually be diagnosed as a lymphoma.

*This partial classification and the complete one at the end of this chapter are modified from the one listed by Walter F. Lever and Gundula Schaumberg-Lever. Histopathology of the skin, ed 8. Philadelphia, JB Lippincott, 1997.

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