Polymorphous Group

1.Hodgkin's disease. Specific lesions are very rare, but nonspecific dermatoses are rather commonly seen. *2. Mycosis fungoides a.Sezary's syndrome: This is a very rare form of exfoliative dermatitis (see Chap..23) that occurs at an early stage of a lymphoma. It is diagnosed by finding unusually large monocytoid cells (so-called Sezary cells) in the blood and in the skin. This cell is indistinguishable from the mycosis cell, both of which are derived from the T cell.

1. Leukemia: refers to circulating abnormal blood cells; may be seen along with lymphomas, but it is almost always associated with myelosis, such as myeloid leukemia. Cutaneous lesions are quite uncommon but may be specific or nonspecific.


A benign, localized erythematous, nodular dermatosis usually on the face, with clinical and histologic features that make a distinction from lymphoma difficult. Some cases may eventually be diagnosed as a lymphoma.

*This partial classification and the complete one at the end of this chapter are modified from the one listed by Walter F. Lever and Gundula Schaumberg-Lever. Histopathology of the skin, ed 8. Philadelphia, JB Lippincott, 1997.

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