Creutzfeldt Jakob disease

Natural Insomnia Program

Insomnia Holistic Treatments Ebook

Get Instant Access

This is usually sporadic, but is occasionally familial. It is due to the same codon 178 mutation as in fatal familial insomnia, but polymorphism at other codons, such as 129, leads to a different phenotypic expression of the genetic abnormality. The cerebral cortex is usually predominantly affected, but in a subtype of the disease there is extensive thalamic atrophy. In these subjects insomnia is a prominent feature, in addition to the dementia and motor abnormalities. There is a progressive loss of both NREM and REM sleep with absence of spindles and K-complexes, and eventually there is no recognizable NREM or REM sleep.

Was this article helpful?

0 0
Wake Up Now

Wake Up Now

For Those Who Can’t Wake Up On Time And Fatigue Throughout The Day. Now You Can Wake Up Early And Be Super Energetic Everyday.

Get My Free Ebook


Post a comment