Strychnine is an alkaloid extracted from the seeds of Strychnos nux-vomica. It was the most commonly prescribed drug in the UK until the early 1920s and was used as a 'tonic' to improve alertness, sensory acuity and wakefulness. It has fallen out of use and is almost never prescribed.

Strychnine abolishes CNS inhibitory postsynaptic potentials due to the release of taurine as a neuro-transmitter and thereby reduces inhibition of reflexes. In overdose it causes muscle spasms, fits and death, although these actions can be antagonized by barbiturates. It has a poor toxic to therapeutic ratio and is usually fatal in a dose of 60-90 mg.

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Sleeping Sanctuary

Sleeping Sanctuary

Salvation For The Sleep Deprived The Ultimate Guide To Sleeping, Napping, Resting And  Restoring Your Energy. Of the many things that we do just instinctively and do not give much  of a thought to, sleep is probably the most prominent one. Most of us sleep only because we have to. We sleep because we cannot stay awake all 24 hours in the day.

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