Use of streptomycin in areas of high HIV prevalence

° In populations with high TB/HIV prevalence, overcrowding is common in TB wards. The staff workload is high, motivation may be poor and resources may be insufficient. This may result in inadequate sterilization of needles and syringes used for streptomycin injections. Without rigorous sterilization, there is a risk of transmission of HIV and other bloodborne pathogens between patients. ° Streptomycin injections are very painful in wasted HIV-infected TB patients.

° Many NTPs now recommend the use of ethambutol in place of streptomycin.

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