* TB meningitis (decreased consciousness, neurological defects, or spinal block).
* TB pericarditis (with effusion or constriction).
* TB pleural effusion (when large with severe symptoms).
* TB laryngitis (with life-threatening airway obstruction).
* Severe hypersensitivity reactions to anti-TB drugs.
* Renal tract TB (to prevent ureteric scarring).
* Massive lymph node enlargement with pressure effects.
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